000 01555nam a2200157Ia 4500
005 20241211205653.0
008 241211s1997 xx 000 0 und d
020 _afcnm2755
082 _a800I/S79
100 _aSteel, Gordon G.
245 0 _aBasic Clinical Radiobiology
260 _c1997
300 _a254 páginas
505 _aIntroduction: the significance of radiobiology for radiotherapy. The growth rate of tumours. Cell proliferation and cellular organization of formal. Proliferative and cellular organization of normal tissues. Radiation response and tolerance of normal tissues. Clonogenic cells and the concepts of cell survival. Models of radiation cell killing. 8.DNA damage and cell killing. 9.Genetic control of the cellular response to ionizing radiation. 10.Dose-response relationships in radiotherapy. 11.Clinical manifestations of normal-tissue damage. 12.Time-dose relationship in radiotherapy. 13.The linear-quadratic approach to fractionation and calculation of isoeffect relationship. 14.Hyperfractionation and accelerated radiotherapy. 15.The oxygen effect. 16.Overcoming hypoxic cell radioressistence. 17.The radiobiology of tumours.The dose rate effect: brachytheratpy. 18.Particle beams in radiotherapy. 19.Particle beams in radiotherapy. 20.Combination of radiotherapy and chemotherapy: principles. 21.Combined radiotherapy and chemotherapy: clinical applications and evaluation. 22.Re-treatment tolerance of normal tissues. 23.Hyperthermia. 24.Targeted radiotherapy. 25.Individualization of radiotherapy.
942 _yLIB
999 _c51975
_d51975